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Highly Efficient Retrograde Gene Transfer into Motor Neurons by a Lentiviral Vector Pseudotyped with Fusion Glycoprotein

The development of gene therapy techniques to introduce transgenes that promote neuronal survival and protection provides effective therapeutic approaches for neurological and neurodegenerative diseases. Intramuscular injection of adenoviral and adeno-associated viral vectors, as well as lentiviral...

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Detalles Bibliográficos
Autores principales: Hirano, Miyabi, Kato, Shigeki, Kobayashi, Kenta, Okada, Tomoaki, Yaginuma, Hiroyuki, Kobayashi, Kazuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782444/
https://www.ncbi.nlm.nih.gov/pubmed/24086660
http://dx.doi.org/10.1371/journal.pone.0075896