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Highly Efficient Retrograde Gene Transfer into Motor Neurons by a Lentiviral Vector Pseudotyped with Fusion Glycoprotein
The development of gene therapy techniques to introduce transgenes that promote neuronal survival and protection provides effective therapeutic approaches for neurological and neurodegenerative diseases. Intramuscular injection of adenoviral and adeno-associated viral vectors, as well as lentiviral...
Autores principales: | Hirano, Miyabi, Kato, Shigeki, Kobayashi, Kenta, Okada, Tomoaki, Yaginuma, Hiroyuki, Kobayashi, Kazuto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782444/ https://www.ncbi.nlm.nih.gov/pubmed/24086660 http://dx.doi.org/10.1371/journal.pone.0075896 |
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