Simvastatin Enhances Protection against Listeria monocytogenes Infection in Mice by Counteracting Listeria-Induced Phagosomal Escape

Statins are well-known cholesterol lowering drugs targeting HMG-CoA-reductase, reducing the risk of coronary disorders and hypercholesterolemia. Statins are also involved in immunomodulation, which might influence the outcome of bacterial infection. Hence, a possible effect of statin treatment on Li...

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Detalles Bibliográficos
Autores principales: Parihar, Suraj P., Guler, Reto, Lang, Dirk M., Suzuki, Harukazu, Marais, A. David, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782446/
https://www.ncbi.nlm.nih.gov/pubmed/24086542
http://dx.doi.org/10.1371/journal.pone.0075490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782446/
https://www.ncbi.nlm.nih.gov/pubmed/24086542
http://dx.doi.org/10.1371/journal.pone.0075490

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