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Simvastatin Enhances Protection against Listeria monocytogenes Infection in Mice by Counteracting Listeria-Induced Phagosomal Escape
Statins are well-known cholesterol lowering drugs targeting HMG-CoA-reductase, reducing the risk of coronary disorders and hypercholesterolemia. Statins are also involved in immunomodulation, which might influence the outcome of bacterial infection. Hence, a possible effect of statin treatment on Li...
Autores principales: | Parihar, Suraj P., Guler, Reto, Lang, Dirk M., Suzuki, Harukazu, Marais, A. David, Brombacher, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782446/ https://www.ncbi.nlm.nih.gov/pubmed/24086542 http://dx.doi.org/10.1371/journal.pone.0075490 |
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