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MicroRNA-150 Expression Induces Myeloid Differentiation of Human Acute Leukemia Cells and Normal Hematopoietic Progenitors

In acute myeloid leukemia (AML) and blast crisis (BC) chronic myeloid leukemia (CML) normal differentiation is impaired. Differentiation of immature stem/progenitor cells is critical for normal blood cell function. MicroRNAs (miRNAs or miRs) are small non-coding RNAs that interfere with gene express...

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Detalles Bibliográficos
Autores principales: Morris, Valerie A., Zhang, Ailin, Yang, Taimei, Stirewalt, Derek L., Ramamurthy, Ranjani, Meshinchi, Soheil, Oehler, Vivian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782459/
https://www.ncbi.nlm.nih.gov/pubmed/24086639
http://dx.doi.org/10.1371/journal.pone.0075815