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Gfi1 and Gfi1b Repress Rag Transcription in Plasmacytoid Dendritic Cells In Vitro

Growth factor independence genes (Gfi1 and Gfi1b) repress recombination activating genes (Rag) transcription in developing B lymphocytes. Because all blood lineages originate from hematopoietic stem cells (HSCs) and different lineage progenitors have been shown to share transcription factor networks...

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Detalles Bibliográficos
Autores principales: Chow, Kwan T., Schulz, Danae, McWhirter, Sarah M., Schlissel, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782466/
https://www.ncbi.nlm.nih.gov/pubmed/24086657
http://dx.doi.org/10.1371/journal.pone.0075891