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Association of p62/SQSTM1 Excess and Oral Carcinogenesis

p62/SQSTM1 (sequestosome1) has never been evaluated in oral epithelium. In order to clarify the role of p62/SQSTM1 in carcinogenesis in oral epithelium, both p62/SQSTM1 and Nrf2 were immunohistochemically evaluated in 54 carcinomas and 14 low grade dysplasias. p62/SQSTM1 knockdowns were also designe...

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Detalles Bibliográficos
Autores principales: Inui, Takuma, Chano, Tokuhiro, Takikita-Suzuki, Mikiko, Nishikawa, Masanori, Yamamoto, Gaku, Okabe, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782476/
https://www.ncbi.nlm.nih.gov/pubmed/24086340
http://dx.doi.org/10.1371/journal.pone.0074398