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Origins of Myc Proteins – Using Intrinsic Protein Disorder to Trace Distant Relatives

Mammalian Myc proteins are important determinants of cell proliferation as well as the undifferentiated state of stem cells and their activity is frequently deregulated in cancer. Based mainly on conservation in the C-terminal DNA-binding and dimerization domain, Myc-like proteins have been reported...

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Detalles Bibliográficos
Autores principales: Mahani, Amir, Henriksson, Johan, Wright, Anthony P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782479/
https://www.ncbi.nlm.nih.gov/pubmed/24086436
http://dx.doi.org/10.1371/journal.pone.0075057