Disrupting the Oncogenic Synergism between Nucleolin and Ras Results in Cell Growth Inhibition and Cell Death

BACKGROUND: The ErbB receptors, Ras proteins and nucleolin are major contributors to malignant transformation. The pleiotropic protein nucleolin can bind to both Ras protein and ErbB receptors. Previously, we have demonstrated a crosstalk between Ras, nucleolin and the ErbB1 receptor. Activated Ras...

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Detalles Bibliográficos
Autores principales: Schokoroy, Sari, Juster, Dolly, Kloog, Yoel, Pinkas-Kramarski, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782480/
https://www.ncbi.nlm.nih.gov/pubmed/24086490
http://dx.doi.org/10.1371/journal.pone.0075269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782480/
https://www.ncbi.nlm.nih.gov/pubmed/24086490
http://dx.doi.org/10.1371/journal.pone.0075269

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