Interferon γ-induced intratumoral expression of CXCL9 alters the local distribution of T cells following immunotherapy with Listeria monocytogenes

The ability of Listeria monocytogenes-based anticancer vaccines to induce tumor regression depends on the responsiveness of malignant cells to interferon γ (IFNγ). Inhibition of IFNγ limits the recruitment of T cells to the tumors of vaccinated mice. We hypothesized that vaccination with immunothera...

Descripción completa

Detalles Bibliográficos
Autores principales: Guirnalda, Patrick, Wood, Laurence, Goenka, Radhika, Crespo, Joel, Paterson, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782529/
https://www.ncbi.nlm.nih.gov/pubmed/24083082
http://dx.doi.org/10.4161/onci.25752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782529/
https://www.ncbi.nlm.nih.gov/pubmed/24083082
http://dx.doi.org/10.4161/onci.25752

Ejemplares similares