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Interferon γ-induced intratumoral expression of CXCL9 alters the local distribution of T cells following immunotherapy with Listeria monocytogenes
The ability of Listeria monocytogenes-based anticancer vaccines to induce tumor regression depends on the responsiveness of malignant cells to interferon γ (IFNγ). Inhibition of IFNγ limits the recruitment of T cells to the tumors of vaccinated mice. We hypothesized that vaccination with immunothera...
Autores principales: | Guirnalda, Patrick, Wood, Laurence, Goenka, Radhika, Crespo, Joel, Paterson, Yvonne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782529/ https://www.ncbi.nlm.nih.gov/pubmed/24083082 http://dx.doi.org/10.4161/onci.25752 |
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