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Sirtuins in neurodegenerative diseases: an update on potential mechanisms

Silent information regulator 2 proteins (sirtuins or SIRTs) are a group of deacetylases (or deacylases) whose activities are dependent on and regulated by nicotinamide adenine dinucleotide (NAD(+)). Compelling evidence supports that sirtuins play major roles in many aspects of physiology, especially...

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Detalles Bibliográficos
Autores principales: Min, Sang-Won, Sohn, Peter D., Cho, Seo-Hyun, Swanson, Raymond A., Gan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782645/
https://www.ncbi.nlm.nih.gov/pubmed/24093018
http://dx.doi.org/10.3389/fnagi.2013.00053