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The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S

Microglia are thought to play important roles in the maintenance of neuronal circuitry and the regulation of behavior. We found that the cortical microglia contain an intrinsic molecular clock and exhibit a circadian expression of cathepsin S (CatS), a microglia-specific lysosomal cysteine protease...

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Detalles Bibliográficos
Autores principales: Hayashi, Yoshinori, Koyanagi, Satoru, Kusunose, Naoki, Okada, Ryo, Wu, Zhou, Tozaki-Saitoh, Hidetoshi, Ukai, Kiyoharu, Kohsaka, Shinichi, Inoue, Kazuhide, Ohdo, Shigehiro, Nakanishi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783043/
https://www.ncbi.nlm.nih.gov/pubmed/24067868
http://dx.doi.org/10.1038/srep02744