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The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S
Microglia are thought to play important roles in the maintenance of neuronal circuitry and the regulation of behavior. We found that the cortical microglia contain an intrinsic molecular clock and exhibit a circadian expression of cathepsin S (CatS), a microglia-specific lysosomal cysteine protease...
Autores principales: | Hayashi, Yoshinori, Koyanagi, Satoru, Kusunose, Naoki, Okada, Ryo, Wu, Zhou, Tozaki-Saitoh, Hidetoshi, Ukai, Kiyoharu, Kohsaka, Shinichi, Inoue, Kazuhide, Ohdo, Shigehiro, Nakanishi, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783043/ https://www.ncbi.nlm.nih.gov/pubmed/24067868 http://dx.doi.org/10.1038/srep02744 |
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