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Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators
Mendelian randomization (MR) is a method for estimating the causal relationship between an exposure and an outcome using a genetic factor as an instrumental variable (IV) for the exposure. In the traditional MR setting, data on the IV, exposure, and outcome are available for all participants. Howeve...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783091/ https://www.ncbi.nlm.nih.gov/pubmed/23863760 http://dx.doi.org/10.1093/aje/kwt084 |