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Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators

Mendelian randomization (MR) is a method for estimating the causal relationship between an exposure and an outcome using a genetic factor as an instrumental variable (IV) for the exposure. In the traditional MR setting, data on the IV, exposure, and outcome are available for all participants. Howeve...

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Detalles Bibliográficos
Autores principales:	Pierce, Brandon L., Burgess, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Practice of Epidemiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783091/ https://www.ncbi.nlm.nih.gov/pubmed/23863760 http://dx.doi.org/10.1093/aje/kwt084

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