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Could yeast prion domains originate from polyQ/N tracts?

A significant body of evidence shows that polyglutamine (polyQ) tracts are important for various biological functions. The characteristic polymorphism of polyQ length is thought to play an important role in the adaptation of organisms to their environment. However, proteins with expanded polyQ are p...

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Detalles Bibliográficos
Autores principales: Alexandrov, Alexander I., Ter-Avanesyan, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783105/
https://www.ncbi.nlm.nih.gov/pubmed/23764835
http://dx.doi.org/10.4161/pri.24628