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Rationally designed coiled-coil DNA looping peptides control DNA topology

Artificial DNA looping peptides were engineered to study the roles of protein and DNA flexibility in controlling the geometry and stability of protein-mediated DNA loops. These LZD (leucine zipper dual-binding) peptides were derived by fusing a second, C-terminal, DNA-binding region onto the GCN4 bZ...

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Detalles Bibliográficos
Autores principales: Gowetski, Daniel B., Kodis, Erin J., Kahn, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783159/
https://www.ncbi.nlm.nih.gov/pubmed/23825092
http://dx.doi.org/10.1093/nar/gkt553