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Dissecting cancer heterogeneity with a probabilistic genotype-phenotype model
One of the obstacles hindering a better understanding of cancer is its heterogeneity. However, computational approaches to model cancer heterogeneity have lagged behind. To bridge this gap, we have developed a new probabilistic approach that models individual cancer cases as mixtures of subtypes. Ou...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783162/ https://www.ncbi.nlm.nih.gov/pubmed/23821670 http://dx.doi.org/10.1093/nar/gkt577 |