DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons but also regulates the abundance of cellular RNAs. We sought to identify transcripts that are regulated by two novel NMD factors, DHX34 and neuroblastoma amplified sequence (NBAS), which...

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Detalles Bibliográficos
Autores principales: Longman, Dasa, Hug, Nele, Keith, Marianne, Anastasaki, Corina, Patton, E. Elizabeth, Grimes, Graeme, Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783168/
https://www.ncbi.nlm.nih.gov/pubmed/23828042
http://dx.doi.org/10.1093/nar/gkt585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783168/
https://www.ncbi.nlm.nih.gov/pubmed/23828042
http://dx.doi.org/10.1093/nar/gkt585

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