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DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans
The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons but also regulates the abundance of cellular RNAs. We sought to identify transcripts that are regulated by two novel NMD factors, DHX34 and neuroblastoma amplified sequence (NBAS), which...
Autores principales: | Longman, Dasa, Hug, Nele, Keith, Marianne, Anastasaki, Corina, Patton, E. Elizabeth, Grimes, Graeme, Cáceres, Javier F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783168/ https://www.ncbi.nlm.nih.gov/pubmed/23828042 http://dx.doi.org/10.1093/nar/gkt585 |
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