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Estrogen represses gene expression through reconfiguring chromatin structures

Estrogen regulates over a thousand genes, with an equal number of them being induced or repressed. The distinct mechanisms underlying these dual transcriptional effects remain largely unknown. We derived comprehensive views of the transcription machineries assembled at estrogen-responsive genes thro...

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Detalles Bibliográficos
Autores principales: Osmanbeyoglu, Hatice Ulku, Lu, Kevin N., Oesterreich, Steffi, Day, Roger S., Benos, Panayiotis V., Coronnello, Claudia, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783169/
https://www.ncbi.nlm.nih.gov/pubmed/23821662
http://dx.doi.org/10.1093/nar/gkt586