Cargando…

Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis

Interferons (IFN) play a pivotal role in innate immunity, orchestrating a cell-intrinsic anti-pathogenic state and stimulating adaptive immune responses. The complex interplay between the primary response to IFNs and its modulation by positive and negative feedback loops is incompletely understood....

Descripción completa

Detalles Bibliográficos
Autores principales: Trilling, Mirko, Bellora, Nicolás, Rutkowski, Andrzej J., de Graaf, Miranda, Dickinson, Paul, Robertson, Kevin, Prazeres da Costa, Olivia, Ghazal, Peter, Friedel, Caroline C., Albà, M. Mar, Dölken, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783172/
https://www.ncbi.nlm.nih.gov/pubmed/23832230
http://dx.doi.org/10.1093/nar/gkt589