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Time-dependent bending rigidity and helical twist of DNA by rearrangement of bound HU protein

HU is a protein that plays a role in various bacterial processes including compaction, transcription and replication of the genome. Here, we use atomic force microscopy to study the effect of HU on the stiffness and supercoiling of double-stranded DNA. First, we measured the persistence length, heig...

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Detalles Bibliográficos
Autores principales: Kundukad, Binu, Cong, Piewen, van der Maarel, Johan R. C., Doyle, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783175/
https://www.ncbi.nlm.nih.gov/pubmed/23828037
http://dx.doi.org/10.1093/nar/gkt593