Estrogen receptor α can selectively repress dioxin receptor-mediated gene expression by targeting DNA methylation

Selective inhibitory crosstalk has been known to occur within the signaling pathways of the dioxin (AhR) and estrogen (ERα) receptors. More specifically, ERα represses a cytochrome P450-encoding gene (CYP1A1) that converts cellular estradiol into a metabolite that inhibits the cell cycle, while it h...

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Detalles Bibliográficos
Autores principales: Marques, Maud, Laflamme, Liette, Gaudreau, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783176/
https://www.ncbi.nlm.nih.gov/pubmed/23828038
http://dx.doi.org/10.1093/nar/gkt595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783176/
https://www.ncbi.nlm.nih.gov/pubmed/23828038
http://dx.doi.org/10.1093/nar/gkt595

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