Widespread purifying selection on RNA structure in mammals

Evolutionarily conserved RNA secondary structures are a robust indicator of purifying selection and, consequently, molecular function. Evaluating their genome-wide occurrence through comparative genomics has consistently been plagued by high false-positive rates and divergent predictions. We present...

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Detalles Bibliográficos
Autores principales: Smith, Martin A., Gesell, Tanja, Stadler, Peter F., Mattick, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783177/
https://www.ncbi.nlm.nih.gov/pubmed/23847102
http://dx.doi.org/10.1093/nar/gkt596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783177/
https://www.ncbi.nlm.nih.gov/pubmed/23847102
http://dx.doi.org/10.1093/nar/gkt596

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