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Widespread purifying selection on RNA structure in mammals

Evolutionarily conserved RNA secondary structures are a robust indicator of purifying selection and, consequently, molecular function. Evaluating their genome-wide occurrence through comparative genomics has consistently been plagued by high false-positive rates and divergent predictions. We present...

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Detalles Bibliográficos
Autores principales:	Smith, Martin A., Gesell, Tanja, Stadler, Peter F., Mattick, John S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783177/ https://www.ncbi.nlm.nih.gov/pubmed/23847102 http://dx.doi.org/10.1093/nar/gkt596

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