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Graph-based modeling of tandem repeats improves global multiple sequence alignment

Tandem repeats (TRs) are often present in proteins with crucial functions, responsible for resistance, pathogenicity and associated with infectious or neurodegenerative diseases. This motivates numerous studies of TRs and their evolution, requiring accurate multiple sequence alignment. TRs may be lo...

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Detalles Bibliográficos
Autores principales: Szalkowski, Adam M., Anisimova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783189/
https://www.ncbi.nlm.nih.gov/pubmed/23877246
http://dx.doi.org/10.1093/nar/gkt628