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An efficient strategy for TALEN-mediated genome engineering in Drosophila

In reverse genetics, a gene’s function is elucidated through targeted modifications in the coding region or associated DNA cis-regulatory elements. To this purpose, recently developed customizable transcription activator-like effector nucleases (TALENs) have proven an invaluable tool, allowing intro...

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Detalles Bibliográficos
Autores principales: Katsuyama, Tomonori, Akmammedov, Arslan, Seimiya, Makiko, Hess, Samuel C., Sievers, Cem, Paro, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783190/
https://www.ncbi.nlm.nih.gov/pubmed/23877243
http://dx.doi.org/10.1093/nar/gkt638