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TrAp: a tree approach for fingerprinting subclonal tumor composition

Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in metastatic tumors. Sequencing technologies provide only an overview of the aggregate of numerous cells. Computational app...

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Detalles Bibliográficos
Autores principales: Strino, Francesco, Parisi, Fabio, Micsinai, Mariann, Kluger, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783191/
https://www.ncbi.nlm.nih.gov/pubmed/23892400
http://dx.doi.org/10.1093/nar/gkt641