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A genome-wide screen for identifying all regulators of a target gene

We have developed a new screening methodology for identifying all genes that control the expression of a target gene through genetic or metabolic interactions. The screen combines mutant libraries with luciferase reporter constructs, whose expression can be monitored in vivo and over time in differe...

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Detalles Bibliográficos
Autores principales: Baptist, Guillaume, Pinel, Corinne, Ranquet, Caroline, Izard, Jérôme, Ropers, Delphine, de Jong, Hidde, Geiselmann, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783194/
https://www.ncbi.nlm.nih.gov/pubmed/23892289
http://dx.doi.org/10.1093/nar/gkt655