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IL-1Β Enriched Monocytes Mount Massive IL-6 Responses to Common Inflammatory Triggers among Chronically HIV-1 Infected Adults on Stable Anti-Retroviral Therapy at Risk for Cardiovascular Disease

Chronic infection by HIV increases the risk of cardiovascular disease (CVD) despite effective antiretroviral therapy (ART). The mechanisms linking HIV to CVD have yet to be fully elucidated. High plasma levels of the pro-inflammatory cytokine IL-6, which may be triggered by IL-1β, is a biomarker of...

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Detalles Bibliográficos
Autores principales: Jalbert, Emilie, Crawford, Timothy Q., D’Antoni, Michelle L., Keating, Sheila M., Norris, Philip J., Nakamoto, Beau K., Seto, Todd, Parikh, Nisha I., Shikuma, Cecilia M., Ndhlovu, Lishomwa C., Barbour, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783392/
https://www.ncbi.nlm.nih.gov/pubmed/24086545
http://dx.doi.org/10.1371/journal.pone.0075500