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Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells

The Hedgehog (HH) signaling pathway is critical for normal embryonic development, tissue patterning and cell differentiation. Aberrant HH signaling is involved in multiple human cancers. HH signaling involves a multi-protein cascade activating the GLI proteins that transcriptionally regulate HH targ...

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Detalles Bibliográficos
Autores principales: Mazumdar, Tapati, Sandhu, Ranjodh, Qadan, Maha, DeVecchio, Jennifer, Magloire, Victoria, Agyeman, Akwasi, Li, Bibo, Houghton, Janet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783395/
https://www.ncbi.nlm.nih.gov/pubmed/24086482
http://dx.doi.org/10.1371/journal.pone.0075253