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Identification of an Enhancer That Increases miR-200b~200a~429 Gene Expression in Breast Cancer Cells

The miR-200b~200a~429 gene cluster is a key regulator of EMT and cancer metastasis, however the transcription-based mechanisms controlling its expression during this process are not well understood. We have analyzed the miR-200b~200a~429 locus for epigenetic modifications in breast epithelial and me...

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Detalles Bibliográficos
Autores principales: Attema, Joanne L., Bert, Andrew G., Lim, Yat-Yuen, Kolesnikoff, Natasha, Lawrence, David M., Pillman, Katherine A., Smith, Eric, Drew, Paul A., Khew-Goodall, Yeesim, Shannon, Frances, Goodall, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783398/
https://www.ncbi.nlm.nih.gov/pubmed/24086551
http://dx.doi.org/10.1371/journal.pone.0075517