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Genetic Variants of Coagulation Factor XI Show Association with Ischemic Stroke Up to 70 Years of Age

BACKGROUND AND PURPOSE: Coagulation factor XI (FXI) has an important role in the propagation and stabilization of a thrombus upon vessel injury. High FXI levels have been implicated in thrombotic diseases including ischemic stroke. The aim of our study was to investigate whether FXI gene (F11) varia...

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Detalles Bibliográficos
Autores principales: Hanson, Ellen, Nilsson, Staffan, Jood, Katarina, Norrving, Bo, Engström, Gunnar, Blomstrand, Christian, Lindgren, Arne, Melander, Olle, Jern, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783404/
https://www.ncbi.nlm.nih.gov/pubmed/24086496
http://dx.doi.org/10.1371/journal.pone.0075286