An important role for Cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors

Mice with a mutation in the Clock gene (ClockΔ19) have been identified as a model of mania, however, the mechanisms that underlie this phenotype, and the changes in the brain that are necessary for lithium’s effectiveness on these mice remain unclear. Here we find that Cholecystokinin(Cck) is a dire...

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Detalles Bibliográficos
Autores principales: Arey, Rachel N., Enwright, John F., Spencer, Sade M., Falcon, Edgardo, Ozburn, Angela R., Ghose, Subroto, Tamminga, Carol, McClung, Colleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783638/
https://www.ncbi.nlm.nih.gov/pubmed/23399917
http://dx.doi.org/10.1038/mp.2013.12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783638/
https://www.ncbi.nlm.nih.gov/pubmed/23399917
http://dx.doi.org/10.1038/mp.2013.12

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