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Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes unveiled by valproate
Valproic acid (VPA) is widely used as an anti-epileptic drug. The primary mechanism of VPA toxicity is interference with mitochondrial beta-oxidation, and it can exacerbate an underlying mitochondrial cytopathy. We report a case of Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783723/ https://www.ncbi.nlm.nih.gov/pubmed/24082934 http://dx.doi.org/10.4103/1817-1745.117847 |