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Dextran Carrier Macromolecules for Colon-specific Delivery of 5-Aminosalicylic Acid

Present manuscript describes the sustained and targeted delivery of 5-aminosalicylic acid to the distal ileum and proximal colon, using dextran (40 kDa) as a carrier for targeting 5-aminosalicylic acid at the colonic site by attaching p-aminobenzoic acid and benzoic acid as linkers. Prepared conjuga...

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Detalles Bibliográficos
Autores principales: Shrivastava, P. K., Shrivastava, A., Sinha, S. K., Shrivastava, S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783745/
https://www.ncbi.nlm.nih.gov/pubmed/24082343
http://dx.doi.org/10.4103/0250-474X.117420