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Immunohistochemical evaluation of oral epithelial dysplasia using cyclin-D1, p27 and p63 expression as predictors of malignant transformation

OBJECTIVE: To evaluate the degree of expression of cyclin-D1, p27 and p63 in mild, moderate and severe dysplasia using immunohistochemical evaluation in order to illustrate their prognostic value and attempt to propose a molecular grading system for oral epithelial dysplasia. MATERIALS AND METHODS:...

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Detalles Bibliográficos
Autores principales: Ramasubramanian, Abilasha, Ramani, Pratibha, Sherlin, Herald J., Premkumar, Priya, Natesan, Anuja, Thiruvengadam, Chandrasekar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783779/
https://www.ncbi.nlm.nih.gov/pubmed/24082731
http://dx.doi.org/10.4103/0976-9668.117011