Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction

The RON receptor tyrosine kinase, a member of the MET proto-oncogene family, is a pathogenic factor implicated in tumor malignancy. Specifically, aberrations in RON signaling result in increased cancer cell growth, survival, invasion, angiogenesis, and drug resistance. Biochemical events such as lig...

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Detalles Bibliográficos
Autores principales: Wang, Ming-Hai, Zhang, Ruiwen, Zhou, Yong-Qing, Yao, Hang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2013
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783819/
https://www.ncbi.nlm.nih.gov/pubmed/24086167
http://dx.doi.org/10.7555/JBR.27.20130038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783819/
https://www.ncbi.nlm.nih.gov/pubmed/24086167
http://dx.doi.org/10.7555/JBR.27.20130038

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