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Martentoxin, a large-conductance Ca(2+)-activated K(+) channel inhibitor, attenuated TNF-α-induced nitric oxide release by human umbilical vein endothelial cells

Martentoxin, a 4,046 Da polypeptide toxin purified from the venom of the scorpion Buthus martensii Karsch, has been demonstrated to block large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels; however, its biological roles are still largely unknown. In the present study, we investigated the phar...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Qian, Wenyi, Zhu, Qing, Chen, Jian, Huan, Fei, Gao, Rong, Xiao, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783824/
https://www.ncbi.nlm.nih.gov/pubmed/24086172
http://dx.doi.org/10.7555/JBR.27.20120080