Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation

Sonic Hedgehog (Shh/GLI) and EGFR signaling pathways modulate Neural Stem Cell (NSC) proliferation. How these signals cooperate is therefore critical for understanding normal brain development and function. Here we report a novel acute effect of Shh signaling on EGFR function. We show that during la...

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Detalles Bibliográficos
Autores principales: Reinchisi, Gisela, Parada, Margarita, Lois, Pablo, Oyanadel, Claudia, Shaughnessy, Ronan, Gonzalez, Alfonso, Palma, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783837/
https://www.ncbi.nlm.nih.gov/pubmed/24133411
http://dx.doi.org/10.3389/fncel.2013.00166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783837/
https://www.ncbi.nlm.nih.gov/pubmed/24133411
http://dx.doi.org/10.3389/fncel.2013.00166

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