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Neurites containing the neurofilament-triplet proteins are selectively vulnerable to cytoskeletal pathology in Alzheimer’s disease and transgenic mouse models

Amyloid-β plaque accumulation in Alzheimer’s disease (AD) is associated with dystrophic neurite (DN) formation and synapse loss in principal neurons, but interneuron pathology is less clearly characterized. We compared the responses of neuronal processes immunoreactive for either neurofilament tripl...

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Detalles Bibliográficos
Autores principales: Mitew, Stanislaw, Kirkcaldie, Matthew T. K., Dickson, Tracey C., Vickers, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783838/
https://www.ncbi.nlm.nih.gov/pubmed/24133416
http://dx.doi.org/10.3389/fnana.2013.00030