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How Numbers, Nature, and Immune Status of Foxp3(+) Regulatory T-Cells Shape the Early Immunological Events in Tumor Development
The influence of CD4(+)CD25(+)Foxp3(+) regulatory T-cells (Tregs) on cancer progression has been demonstrated in a large number of preclinical models and confirmed in several types of malignancies. Neoplastic processes trigger an increase of Treg numbers in draining lymph nodes, spleen, blood, and t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784046/ https://www.ncbi.nlm.nih.gov/pubmed/24133490 http://dx.doi.org/10.3389/fimmu.2013.00292 |