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DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease

The central nervous system has a pattern of gene expression that is closely regulated with respect to functional and anatomical regions. DNA methylation is a major regulator of transcriptional activity, and aberrations in the distribution of this epigenetic mark may be involved in many neurological...

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Detalles Bibliográficos
Autores principales: Sanchez-Mut, Jose V., Aso, Ester, Panayotis, Nicolas, Lott, Ira, Dierssen, Mara, Rabano, Alberto, Urdinguio, Rocio G., Fernandez, Agustin F., Astudillo, Aurora, Martin-Subero, Jose I., Balint, Balazs, Fraga, Mario F., Gomez, Antonio, Gurnot, Cecile, Roux, Jean-Christophe, Avila, Jesus, Hensch, Takao K., Ferrer, Isidre, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784285/
https://www.ncbi.nlm.nih.gov/pubmed/24030951
http://dx.doi.org/10.1093/brain/awt237