Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin

Insulin-dependent translocation of glucose transporter 4 (Glut4) to the plasma membrane of fat and skeletal muscle cells plays the key role in postprandial clearance of blood glucose. Glut4 represents the major cell-specific component of the insulin-responsive vesicles (IRVs). It is not clear, howev...

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Detalles Bibliográficos
Autores principales: Huang, Guanrong, Buckler-Pena, Dana, Nauta, Tessa, Singh, Maneet, Asmar, Agnes, Shi, Jun, Kim, Ju Youn, Kandror, Konstantin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784384/
https://www.ncbi.nlm.nih.gov/pubmed/23966466
http://dx.doi.org/10.1091/mbc.E12-10-0765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784384/
https://www.ncbi.nlm.nih.gov/pubmed/23966466
http://dx.doi.org/10.1091/mbc.E12-10-0765

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