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Regulation of ER-phagy by a Ypt/Rab GTPase module

Accumulation of misfolded proteins on intracellular membranes has been implicated in neurodegenerative diseases. One cellular pathway that clears such aggregates is endoplasmic reticulum autophagy (ER-phagy), a selective autophagy pathway that delivers excess ER to the lysosome for degradation. Not...

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Detalles Bibliográficos
Autores principales: Lipatova, Zhanna, Shah, Ankur H., Kim, Jane J., Mulholland, Jonathan W., Segev, Nava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784386/
https://www.ncbi.nlm.nih.gov/pubmed/23924895
http://dx.doi.org/10.1091/mbc.E13-05-0269