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Initial activation of STIM1, the regulator of store-operated calcium entry
Physiological Ca(2+) signalling in T lymphocytes and other cells depends on the STIM-ORAI pathway of store-operated Ca(2+) entry. STIM1 and STIM2 are Ca(2+) sensors located in the endoplasmic reticulum (ER) membrane, with ER-luminal domains that monitor cellular Ca(2+) stores and cytoplasmic domains...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784406/ https://www.ncbi.nlm.nih.gov/pubmed/23851458 http://dx.doi.org/10.1038/nsmb.2625 |