Smad2-Dependent Downregulation of miR-30 Is Required for TGF-β-Induced Apoptosis in Podocytes

Transforming growth factors beta (TGF-β) are multi-functional cytokines capable of inducing apoptosis in epithelial cells, including glomerular podocytes. We and others have previously shown that podocyte-selective genetic deletion of the microRNA (miR)-processing enzyme, Dicer, caused glomeruloscle...

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Detalles Bibliográficos
Autores principales: Shi, Shaolin, Yu, Liping, Zhang, Taoran, Qi, Haiying, Xavier, Sandhya, Ju, Wenjun, Bottinger, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784460/
https://www.ncbi.nlm.nih.gov/pubmed/24086574
http://dx.doi.org/10.1371/journal.pone.0075572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784460/
https://www.ncbi.nlm.nih.gov/pubmed/24086574
http://dx.doi.org/10.1371/journal.pone.0075572

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