Assisted Evolution Enables HIV-1 to Overcome a High TRIM5α-Imposed Genetic Barrier to Rhesus Macaque Tropism

Diversification of antiretroviral factors during host evolution has erected formidable barriers to cross-species retrovirus transmission. This phenomenon likely protects humans from infection by many modern retroviruses, but it has also impaired the development of primate models of HIV-1 infection....

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Detalles Bibliográficos
Autores principales: Soll, Steven J., Wilson, Sam J., Kutluay, Sebla B., Hatziioannou, Theodora, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784476/
https://www.ncbi.nlm.nih.gov/pubmed/24086139
http://dx.doi.org/10.1371/journal.ppat.1003667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784476/
https://www.ncbi.nlm.nih.gov/pubmed/24086139
http://dx.doi.org/10.1371/journal.ppat.1003667

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